New PDF release: Amyotrophic Lateral Sclerosis: A Guide for Patients and

By Hiroshi Mitsumoto MD

ISBN-10: 1932603727

ISBN-13: 9781932603729

This significant booklet covers each element of residing with ALS, from medical gains of the disorder to an outline of symptom administration to realizing its analysis. significant sections take care of overseeing therapy and rehabilitation, residing with ALS, the disease’s complicated part, end-of-life concerns, and assets. largely revised and rewritten, this variation includes new chapters at the most up-to-date methods to treating ALS signs, using noninvasive ventilators, multidisciplinary group care, new guidance being constructed by way of the yank Academy of Neurology for sufferers with ALS, using riluzole (Rilutek), and extra.

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Additional info for Amyotrophic Lateral Sclerosis: A Guide for Patients and Families

Example text

Guillain G. Amyotrophic lateral sclerosis. In: Bailey P, trans-ed. -M. Charcot. 1825– 1893 His Life—His Work. New York, NY: Paul B. ; 1959:106–108. 9. Kimura K, Yase Y, Higashi Y, et al. Epidemiological and geomedical studies on amyotrophic lateral sclerosis. Dis Nerv Syst. 1963;24:155–159. 10. Reed DM, Brody JA. Amyotrophic lateral sclerosis and parkinsonism—dementia on Guam, 1945–1972. Am J Epidemiol. 1975;101:287–301. 11. Gajdusek DC. Motor-neuron disease in natives of New Guinea. N Engl J Med.

When only the lower motor neurons are affected, leading to severe wasting and weakness in the muscles with loss of reflexes, the disorder is known as progressive muscular atrophy. The signs of upper motor neuron dysfunction are not noted. This is called lower motor neuron onset ALS, or the progressive muscular atrophy form of ALS. With progressive bulbar palsy, the disorder starts in the muscles of speech and swallowing, causing slurred speech and choking. Patients eventually lose all ability to speak and swallow.

Muscle atrophy can affect any skeletal muscles, but the muscles in the forearms or hands and lower leg and foot muscles (the distal muscles) generally atrophy more often than muscles near the body trunk (the proximal muscles). Hyporeflexia If the disease involves only the lower motor neurons, reflexes that occur when a muscle is stretched are decreased or even absent. This condition is referred to as hyporeflexia and is in contrast to the hyperreflexia that occurs in upper motor neuron dysfunction.

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Amyotrophic Lateral Sclerosis: A Guide for Patients and Families by Hiroshi Mitsumoto MD


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